rs11699

Rs11699 is a single nucleotide polymorphism (SNP) located on chromosome 15. Specifically, it is found within the gene GCKR. GCKR, which stands for glucokinase regulator, plays a role in regulating the activity of glucokinase, an enzyme involved in glucose metabolism. This SNP is a common variant with a known allele frequency in human populations. Research has investigated the association of Rs11699 with various metabolic traits and diseases. Studies have explored its potential links to blood lipid levels, such as triglycerides and HDL cholesterol, as well as its association with type 2 diabetes and related conditions. The specific allele at Rs11699 has been shown in some studies to be associated with altered fasting glucose and insulin levels. However, findings across different populations and studies can vary, and the precise functional impact of this SNP is an ongoing area of research. It is one of many genetic markers that contribute to individual differences in metabolic health.