raltitrexedreduces
Raltitrexed is a chemotherapy drug used in the treatment of certain types of cancer, primarily advanced colorectal cancer. It is an antimetabolite, specifically a thymidylate synthase inhibitor. By blocking the action of the enzyme thymidylate synthase, raltitrexed interferes with the synthesis of thymidine, a crucial component of DNA. This inhibition leads to a depletion of thymidine triphosphate, which is essential for DNA replication and repair, ultimately causing cancer cells to die.
The drug is administered intravenously. Its efficacy in colorectal cancer has been demonstrated in clinical trials,
Raltitrexed's mechanism of action makes it a targeted therapy against rapidly dividing cells, a characteristic of