quinolin

Quinolin, commonly spelled quinoline in English, is an aromatic heterocyclic organic compound with the formula C9H7N. It comprises a benzene ring fused to a pyridine ring, forming a planar bicyclic structure. Quinoline is the simplest member of the quinoline family and serves as a key building block for many derivatives with applications in industry and research.

Quinoline occurs in trace amounts in coal tar and other fossil-derived materials. Industrial supply is provided by extraction from coal tar and by synthetic routes that build the fused ring system, including classical methods such as the Skraup synthesis and contemporary catalytic approaches.

Quinoline and its derivatives have diverse uses. They are employed as solvents and as intermediates in the manufacture of dyes, pigments, and pharmaceuticals. The quinoline nucleus is a common core in biologically active compounds, including antimalarial medicines, and quinoline-based ligands are used in coordination chemistry.

Safety and handling: Quinoline is toxic and can be irritating to skin, eyes, and the respiratory system. It has limited water solubility and is flammable. Proper storage, ventilation, and protective equipment are recommended. Disposal should follow applicable chemical waste regulations due to environmental and health concerns.