presünaptiliselt

Presünaptiliselt is a term used in neuroscience to describe the conditions or characteristics of a neuron before it reaches the synapse, which is the junction where a neuron communicates with another neuron, muscle, or gland. The presynaptic neuron is the neuron that releases neurotransmitters into the synapse, initiating the transmission of a signal to the postsynaptic neuron or target cell.

The presynaptic terminal is the specialized end of the presynaptic neuron that contains the neurotransmitter vesicles, which are small, membrane-bound sacs filled with neurotransmitters. These vesicles fuse with the presynaptic membrane, releasing their contents into the synaptic cleft, a small gap between the presynaptic and postsynaptic neurons. The neurotransmitters then diffuse across the synaptic cleft and bind to receptors on the postsynaptic membrane, triggering a response in the postsynaptic neuron or target cell.

Presünaptiliselt refers to the conditions or characteristics of the presynaptic neuron and its terminal before the neurotransmitters are released. This can include factors such as the number and size of neurotransmitter vesicles, the concentration of neurotransmitters, the presence of neurotransmitter receptors, and the activity of neurotransmitter-synthesizing enzymes. These factors can influence the strength and duration of the synaptic transmission, as well as the overall function of the nervous system.