posttranslaationaalista
Posttranslational modification (PTM) refers to the chemical alteration of proteins after their primary translation from messenger RNA (mRNA) into a polypeptide chain. These modifications occur in the cytoplasm or nucleus of the cell and are crucial for the proper folding, stability, activity, and localization of proteins. PTMs can involve the addition of chemical groups, such as phosphate groups, acetyl groups, or ubiquitin, or the removal of amino acids. They play a significant role in various biological processes, including signal transduction, cell division, and protein degradation.
PTMs can be classified into several categories based on the type of modification and the amino acid
PTMs are tightly regulated and often occur in response to specific signals or cellular conditions. They can