photohalogenation

Photohalogenation is a chemical reaction where a halogen atom, such as chlorine or bromine, is substituted for a hydrogen atom in a molecule. This process is initiated by light, typically ultraviolet (UV) radiation. The light energy is absorbed by the halogen molecule, causing it to break apart into two highly reactive halogen radicals. These radicals then collide with the organic molecule, abstracting a hydrogen atom and forming a hydrogen halide and an alkyl radical. This alkyl radical then reacts with another halogen molecule to form the halogenated product and regenerate a halogen radical, continuing the chain reaction. Photohalogenation is a common method for introducing halogens into organic compounds, particularly alkanes and alkyl side chains of aromatic compounds. The reaction is often non-selective, meaning it can occur at various positions within the molecule, leading to a mixture of products. Control over selectivity can sometimes be achieved by adjusting reaction conditions, such as temperature or the intensity of the light source. Applications include the synthesis of various intermediates used in pharmaceuticals, agrochemicals, and materials science. However, the generation of reactive radicals and the potential for non-specific substitution are factors that need careful consideration during synthetic design.