periostben

Periostben is not a widely recognized term in standard anatomy, biology, or medicine. It may be a misspelling or variant of periosteum or periostin, two distinct concepts in bone biology. This article provides brief overviews of those two possibilities to help readers locate reliable information.

If the intended term is periosteum, periosteum is a dense, vascularized membrane that surrounds bone, except at joint surfaces. It consists of an outer fibrous layer rich in collagen and nerves, and an inner cambium (osteogenic) layer containing progenitor cells. The periosteum anchors tendons and ligaments and supplies blood to cortical bone through its vascular network. It plays a key role in bone growth in thickness, repair after fractures, and the maintenance of bone health. The membrane remains continuous with the periosteum of adjacent bones at sutures and with Sharpey's fibers that embed into the underlying bone matrix.

If the intended term is periostin, periostin is a matricellular protein encoded by the POSTN gene. It is secreted primarily by fibroblasts and osteoblasts and becomes part of the extracellular matrix, where it interacts with integrins to influence cell adhesion, migration, and signaling. In bone biology, periostin supports osteoblast differentiation and fracture healing and participates in tissue remodeling and angiogenesis. It has also been implicated in fibrotic diseases and certain cancers, and mouse models lacking periostin show skeletal abnormalities and impaired fracture repair.

Disambiguation: if you meant another term related to bone or connective tissue, please specify for a more precise article.