osteomalacji
Osteomalacia is a metabolic bone disease characterized by inadequate or delayed mineralization of osteoid, the organic matrix of bone. This results in soft, weak bones that are prone to fracture. In children, the equivalent condition is known as rickets. The primary cause of osteomalacia is a deficiency in vitamin D, which is essential for calcium and phosphate absorption in the intestines. Other contributing factors can include insufficient dietary intake of calcium or phosphate, certain gastrointestinal disorders that impair nutrient absorption, chronic kidney disease which affects vitamin D metabolism and phosphate excretion, and certain medications that interfere with vitamin D or calcium.
Symptoms of osteomalacia can vary and may include bone pain, particularly in the lower back, pelvis, and
Treatment focuses on addressing the underlying cause. This usually involves supplementation with vitamin D and calcium.