ossifikationer

Ossification, also known as ossifications or ossificans, is the natural process by which cartilage or connective tissue gradually turns into bone. This process is fundamental to skeletal development in vertebrates. It begins during embryonic development and continues through childhood and adolescence. There are two main types of ossification: endochondral ossification and intramembranous ossification. Endochondral ossification is responsible for the formation of most of the skeleton, particularly the long bones. It involves a cartilage model that is progressively replaced by bone tissue. Intramembranous ossification, on the other hand, forms bones directly from mesenchymal connective tissue, such as the flat bones of the skull. This process is crucial for bone repair as well, allowing fractures to heal by forming new bone. Factors influencing ossification include hormones, genetics, and mechanical stress. Abnormalities in ossification can lead to various bone disorders.