oglykosülasjon

Oglykosülasjon refers to a type of protein modification where a sugar molecule, or glycan, is attached to a protein. This process is crucial for many biological functions, including protein folding, stability, cell-cell recognition, and immune responses. Glycosylation occurs in the endoplasmic reticulum and Golgi apparatus of eukaryotic cells. There are several types of glycosylation, with the two most common being N-linked and O-linked glycosylation. N-linked glycosylation involves the attachment of a glycan to an asparagine residue within a specific amino acid sequence (Asn-X-Ser/Thr, where X is any amino acid except proline). O-linked glycosylation involves the attachment of a glycan to a serine or threonine residue. The specific type of glycan and its attachment site can significantly alter the protein's properties and function. Aberrant glycosylation patterns have been linked to various diseases, including cancer and inflammatory disorders, making the study of oglykosülasjon important for understanding both normal physiology and pathology.