ofHLA

ofHLA is a Python library designed to facilitate the manipulation and analysis of HLA (Human Leukocyte Antigen) typing data. HLA genes are critical components of the immune system, and accurate typing is essential for various applications, including transplantation, disease association studies, and personalized medicine. The library provides tools for parsing and interpreting HLA typing results from different sources, such as sequencing data or imputation panels. It offers functionalities to standardize nomenclature, resolve ambiguities in typing, and perform statistical analyses related to HLA alleles. The primary goal of ofHLA is to simplify the complex process of working with HLA data, making it more accessible to researchers and clinicians. It aims to reduce errors and improve the consistency of HLA data analysis across different studies. The library supports various HLA locus representations and can handle different levels of typing resolution. Its design emphasizes ease of use and integration with other bioinformatics tools.