närvilihase

Närvilihase, also known as neuromuscular junction, is a specialized synapse where a motor neuron communicates with a muscle fiber. This junction is crucial for voluntary movement, as it allows the nervous system to control muscle contraction. The structure of a närvilihase involves the axon terminal of the motor neuron, the synaptic cleft, and the motor end-plate of the muscle fiber. When a nerve impulse reaches the axon terminal, it triggers the release of neurotransmitters, primarily acetylcholine, into the synaptic cleft. Acetylcholine then binds to receptors on the motor end-plate, initiating a series of events that lead to the depolarization of the muscle fiber membrane. This depolarization, in turn, causes the release of calcium ions within the muscle cell, which are essential for the sliding filament mechanism that generates muscle force and contraction. Dysfunction of the närvilihase can result in various neuromuscular disorders affecting muscle strength and function.