nterminusest

Nterminusest refers to a component of chromosome structure that results from the organizing and packing of chromatin. Chromatin is the substance that makes up chromosomes. Nterminusest is the series of events by which nuclease digestion of chromatin, followed by the analysis of the protein(endpoint), reveals information about the arrangement of nucleosomes at these sites. A nuclease is an enzyme that breaks down DNA effectively.

This process of nuclease digestion results in a "stretched" or denatured chromatin form, creating a network that is easily observable. The same network pattern would be seen in all cells if the Nterminusest were the case. The main use of nterminusest comes in research settings, where the details of how chromatiny is assembled is still not fully understood.

As much is still unknown about Nterminusest, research continues. This includes research aimed specifically at understanding the progression from repair initiation to eventual protein setup.