noradrenalinu
Noradrenalinu, also called noradrenaline or norepinephrine, is a catecholamine that functions as a neurotransmitter in the central and peripheral nervous systems and as a hormone released by the adrenal medulla. It is a key component of the body's response to stress and contributes to the regulation of cardiovascular function and arousal.
Synthesis occurs from the amino acid tyrosine via tyrosine hydroxylase to L-DOPA, then to dopamine, which is
Receptors: NE acts on adrenergic receptors, with strong effects on alpha-1 and beta-1 receptors, inducing vasoconstriction,
Clinical and pharmacological aspects: Endogenous NE helps maintain vascular tone and blood pressure. Pharmacologically, norepinephrine is