neurometabolite

A neurometabolite is a small molecule that is involved in the function or metabolism of the nervous system. These compounds play crucial roles in a wide range of neurological processes, including neurotransmission, energy production, and cellular signaling. Neurometabolites can be broadly categorized based on their function. For example, neurotransmitters, such as glutamate and GABA, are neurometabolites that facilitate communication between neurons. Other neurometabolites are involved in cellular energy metabolism, like lactate and glucose, which provide the fuel for neuronal activity.

The study of neurometabolites is essential for understanding brain health and disease. Alterations in the levels or activity of specific neurometabolites have been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and depression. Techniques like magnetic resonance spectroscopy (MRS) allow researchers to non-invasively measure the concentration of certain neurometabolites in living brains, providing valuable insights into their role in both normal function and pathological states. Advances in analytical chemistry and bioinformatics further aid in the identification and quantification of these vital molecules. The intricate interplay of neurometabolites underscores the complexity of neural circuits and their susceptibility to metabolic disturbances.