nefrotooksiset

Nefrotoksiset refers to substances that are harmful to the kidneys. These substances can cause damage to the kidney cells, impairing their function. The kidneys are vital organs responsible for filtering waste products from the blood, regulating blood pressure, and maintaining electrolyte balance. When damaged, their ability to perform these crucial functions is compromised.

Various agents can be nephrotoxic, including certain medications, heavy metals, and environmental toxins. Some common examples of nephrotoxic drugs include certain antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and chemotherapy agents. The risk of kidney damage from these substances can depend on factors such as the dose, duration of exposure, and individual susceptibility.

Symptoms of kidney damage due to nephrotoxic substances can range from mild to severe. They may include changes in urination frequency, swelling in the legs and feet, fatigue, nausea, and decreased appetite. In more severe cases, acute kidney injury or chronic kidney disease can develop.

Diagnosis of nephrotoxicity typically involves blood and urine tests to assess kidney function. Identifying the causative agent is crucial for managing the condition. Treatment often involves discontinuing the offending substance and supportive care to help the kidneys recover. Prevention strategies include careful monitoring of kidney function in individuals taking potentially nephrotoxic medications and avoiding unnecessary exposure to harmful toxins.