multivesikulaarseid

Multivesikulaarsed literally translates from Estonian to "multivesicular". In biology, the term commonly refers to multivesicular bodies (MVBs). These are endosomal organelles found in eukaryotic cells. MVBs are characterized by their internal structure, which contains multiple small vesicles within a larger limiting membrane. They are crucial components of the endocytic pathway, playing a role in protein sorting and degradation. MVBs are formed from early endosomes and receive cargo from various cellular sources, including the plasma membrane and the Golgi apparatus. Their primary function is to direct internalized molecules to either recycling pathways or to lysosomes for degradation. The process of MVB formation and cargo sorting is complex and involves the ESCRT (endosomal sorting complexes required for transport) machinery. MVBs can also be involved in processes such as viral budding and the release of exosomes, which are small extracellular vesicles released by MVBs. The precise mechanisms and roles of MVBs are still areas of active research.