multientsyymikompleksi

A multienzyme complex, also known as a multi-enzyme system or enzyme aggregate, is a collection of non-covalently bound enzymes that are physically close to each other and often involved in a common metabolic pathway or reaction sequence. These complexes can function as a single unit, facilitating the efficient transfer of intermediates from one enzyme to the next, thereby increasing the overall rate of the reaction and minimizing the diffusion of unstable intermediates.

The proximity of enzymes within a multienzyme complex can also prevent side reactions and improve the specificity of the pathway. The structure of these complexes can vary, from simple associations of two or three enzymes to highly organized structures with many different enzymatic activities. Examples of well-known multienzyme complexes include pyruvate dehydrogenase complex, which is involved in cellular respiration, and fatty acid synthase, responsible for fatty acid synthesis. The formation and dissociation of these complexes can be regulated, allowing cells to control metabolic flux in response to changing conditions. Studying multienzyme complexes is crucial for understanding cellular metabolism and for potential applications in biotechnology, such as the development of artificial enzymes.