monoresistant

Monoresistance refers to a type of antibiotic resistance where a microorganism, typically bacteria, exhibits resistance to only a single class or specific type of antibiotic. This is in contrast to multi-drug resistance, where the organism is resistant to multiple classes of antibiotics. When a bacterium is monoresistant, it means that standard treatments using that particular antibiotic will likely be ineffective. However, other classes of antibiotics may still be effective in treating infections caused by such a monoresistant strain. Identifying monoresistance is crucial for effective treatment as it guides clinicians in selecting appropriate antimicrobial therapy. If a specific antibiotic is known to be ineffective due to monoresistance, a different drug can be chosen, preventing treatment failure and potentially reducing the spread of more extensively resistant strains. The development of monoresistance can occur through genetic mutations or the acquisition of resistance genes, often driven by the selective pressure of antibiotic use.