miR390AGO7

miR390AGO7 is a microRNA-mediated gene regulatory system that plays a crucial role in plant defense and development. Specifically, it is a miRNA (microRNA) known as miR390 that targets a specific gene, TAS3, and its associated protein, AXR7 (also known as AGO7). This regulatory system is conserved across various plant species, including Arabidopsis thaliana and Brassica species.

The miR390AGO7 system is involved in the shoot meristem maintenance and the regulation of shoot root transition. The AGO7 protein is a key component of the RNA-induced silencing complex (RISC), which is responsible for guiding the miR390 to its target gene, TAS3. The interaction between miR390 and AGO7 is crucial for the proper regulation of TAS3's expression and subsequent effects on related genes.

Studies have shown that mutations in miR390 or its associated genes, such as AGO7, result in the de-regulation of TAS3 and subsequent phenotypic variations. This can lead to the disruption of normal shoot development and formation of ectopic roots, among other abnormalities. The miR390AGO7 system serves as a prime example of how microRNA-mediated regulation plays a critical role in confined shoot meristem domain specification and root formation.

Moreover, the miR390AGO7 pathway has been shown to be linked to the salicylic acid pathway (SAG), particularly through Arabidopsis WRKY535 troller, affecting disease resistance and relevant auxin transport. This intricate network highlights the complexity of miRNA-mediated gene regulation in vegetative plant growth and development.

In summary, the miR390AGO7 system is a complex regulatory pathway that has been well-characterized in Arabidopsis. It demonstrates how microRNA-mediated regulation influences both regular plant development and veispel bacterial resistance, and it continues to be studied in the context of plant regulation and evolution.