mg02505
MG02505 is a gene located on chromosome 17q21.31, which encodes for the protein mitogen-activated protein kinase 14 (MAPK14). MAPK14 is a member of the mitogen-activated protein kinase (MAPK) family, which plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. MAPK14 is activated by upstream kinases, such as MAPK3 (ERK2) and MAPK1 (ERK1), and it phosphorylates downstream substrates, such as p38 MAPK and JNK, to regulate their activities.
Mutations in the MAPK14 gene have been associated with several diseases, including cancer and inflammatory disorders.
MG02505 is also a target for drug development, with several small-molecule inhibitors being developed to modulate