lisamolekulide

Lisamolekulide is a naturally occurring secondary metabolite isolated from the marine-derived fungus *Aspergillus* sp. It belongs to the class of compounds known as polyketides, which are characterized by their complex structures and diverse biological activities. The compound was first identified in 2012 through a screening program aimed at discovering novel bioactive substances from marine organisms.

Lisamolekulide exhibits a unique macrocyclic structure featuring a 16-membered ring with multiple hydroxyl and methyl groups. Its molecular formula is C₂₄H₄₂O₁₀, and it has been studied for its potential antimicrobial and cytotoxic properties. Early research suggests that lisamolekulide may inhibit the growth of certain pathogenic bacteria and fungi, though its mechanism of action remains partially understood.

The compound is typically extracted from marine-derived fungal cultures, often collected from marine sediments or associated with marine invertebrates. Due to its limited natural abundance, synthetic approaches have been explored to facilitate further biological evaluation. Lisamolekulide’s structural complexity poses challenges for total synthesis, but progress in this area could enable larger-scale studies.

While lisamolekulide shows promise in preclinical research, its clinical applications have not yet been established. Further investigation is required to elucidate its pharmacological profile, toxicity, and potential therapeutic uses. As with many marine-derived natural products, lisamolekulide represents an important lead compound for drug discovery efforts in antimicrobial and anticancer research.