lipidoidbased
Lipidoidbased refers to materials or systems that are primarily composed of or utilize lipidoids as their core structural or functional component. Lipidoids are a class of synthetic cationic lipids that have gained significant attention in biomedical research, particularly for their application in drug and nucleic acid delivery. These molecules are characterized by a lipid tail, a hydrophilic head group, and a charged moiety, often an amine. Their amphipathic nature allows them to self-assemble into structures, such as liposomes or micelles, which can encapsulate and protect therapeutic payloads like messenger RNA (mRNA) or small interfering RNA (siRNA).
The design of lipidoidbased systems is highly tunable, allowing researchers to modify their chemical structure to