laktoperoxidázového

Laktoperoxidázový refers to the lactoperoxidase enzyme system, a naturally occurring antimicrobial system found in milk and other exocrine secretions. This system is composed of three main components: lactoperoxidase (LPO), thiocyanate (SCN⁻), and hydrogen peroxide (H₂O₂). In the presence of hydrogen peroxide, lactoperoxidase catalyzes the oxidation of thiocyanate to hypothiocyanite (OSCN⁻).

Hypothiocyanite is a potent oxidizing agent that exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses. It exerts its effect by disrupting essential cellular processes, such as enzyme function and cell membrane integrity. The lactoperoxidase system is considered a crucial part of the innate immune defense in mammals, helping to protect against microbial colonization and infection.

The lactoperoxidase system has been explored for various applications due to its antimicrobial properties. It is naturally present in human breast milk, contributing to the protection of nursing infants. In the food industry, it has been used as a natural preservative to extend the shelf life of milk and dairy products without the need for harsh chemicals. Furthermore, it has been investigated for use in oral hygiene products, such as toothpaste and mouthwash, to combat oral bacteria responsible for cavities and gum disease. Its non-toxic nature and natural occurrence make it an attractive alternative to synthetic antimicrobials in certain contexts.