kontaktiinhiboinnin
Kontaktiinhiboinnin, also known as contact inhibition or the McFarland phenomenon, is a biological process that regulates cell growth. It refers to the cessation of cell division when cells come into physical contact with each other. This phenomenon is a crucial mechanism for maintaining tissue structure and preventing uncontrolled proliferation, which is characteristic of cancer.
When cells in a culture dish reach a certain density and touch their neighbors, they typically stop
The loss of contact inhibition is a hallmark of many cancers. Cancer cells often acquire mutations that