komplementvermittelten

Komplementvermittelten is a term used in the field of immunology to describe a type of immune response that is initiated by the activation of the complement system. The complement system is a group of proteins found in the blood and other bodily fluids that play a crucial role in the immune response. When the complement system is activated, it can lead to the destruction of pathogens, such as bacteria and viruses, and the clearance of damaged or dying cells.

The activation of the complement system can occur through two main pathways: the classical pathway and the alternative pathway. The classical pathway is initiated by the binding of antibodies to the surface of a pathogen, while the alternative pathway is initiated by the spontaneous activation of complement proteins. Once activated, the complement system can lead to the formation of a membrane attack complex (MAC), which is a pore-forming complex that can lyse the membrane of the target cell.

Komplementvermittelten is an important component of the innate immune response, which is the first line of defense against pathogens. It works in conjunction with other immune cells, such as phagocytes and natural killer cells, to clear infections and maintain homeostasis in the body. The complement system is also involved in the regulation of inflammation and the clearance of immune complexes, which are aggregates of antibodies and antigens that can contribute to the development of autoimmune diseases.

In summary, Komplementvermittelten refers to the immune response mediated by the complement system, which plays a vital role in the defense against pathogens and the maintenance of immune homeostasis. Its activation can lead to the destruction of pathogens and the clearance of damaged cells, making it an essential component of the innate immune response.