kolangiotsüütideks

Kolangiotsüütideks are cells that line the bile ducts within the liver. These ducts are responsible for transporting bile from the liver to the gallbladder and then to the small intestine, where it aids in digestion. Kolangiotsüütideks play a crucial role in this process by secreting bicarbonate and other substances that help modify the composition of bile. They also contribute to the reabsorption of certain molecules from the bile.

These cells are characterized by their cuboidal or columnar shape and possess microvilli on their apical surface, which is the surface facing the lumen of the bile duct. This structure increases the surface area available for absorption and secretion. Kolangiotsüütideks are dynamic and can respond to various physiological and pathological stimuli. For example, they can proliferate in response to liver injury or bile duct obstruction.

Diseases affecting the bile ducts, such as primary biliary cholangitis or primary sclerosing cholangitis, often involve damage and dysfunction of kolangiotsüütideks. Understanding the normal function and behavior of these cells is therefore essential for diagnosing and treating a range of liver and biliary diseases. Research continues to explore the specific molecular mechanisms governing kolangiotsüütideks function and their involvement in disease pathogenesis.