kadherins
Cadherins are a class of type-I transmembrane proteins that play a crucial role in cell adhesion, a process by which cells interact and bind with each other. They are named for their calcium-dependent adhesion properties, as calcium ions are essential for their proper functioning. Cadherins are found in all animal cells and are vital for the development and maintenance of tissues and organs.
The cadherin family includes several subtypes, such as E-cadherin, N-cadherin, P-cadherin, and VE-cadherin, each with specific
Cadherins have a characteristic structure, consisting of an extracellular domain that mediates cell-cell adhesion, a transmembrane
Dysregulation of cadherin function has been implicated in various diseases, including cancer. Loss of E-cadherin expression,