imetelstat
Imetelstat is a novel therapeutic agent that acts as a telomerase inhibitor. Telomerase is an enzyme crucial for maintaining the telomeres, which are protective caps at the ends of chromosomes. In many cancer cells, telomerase is reactivated, allowing them to divide indefinitely. By inhibiting telomerase, imetelstat aims to prevent cancer cells from replicating and thus halt tumor growth.
This drug is an oligonucleotide, meaning it is a short strand of nucleic acid. Its mechanism of
The development of imetelstat has been driven by the understanding of telomere biology and its role in