hydridedonor
A hydridedonor refers to a chemical species that can readily donate a hydride ion (H⁻). A hydride ion is a hydrogen atom with an extra electron, giving it a negative charge. Hydridedonors are crucial reagents in organic synthesis, particularly in reduction reactions where they transfer a hydride ion to an acceptor molecule, typically a carbonyl compound or an alkene.
Common hydridedonors include metal hydrides such as sodium borohydride (NaBH₄) and lithium aluminum hydride (LiAlH₄). These
The mechanism of hydride transfer generally involves the nucleophilic attack of the hydride ion on an electrophilic