homothreonine

Homothreonine is a non-proteinogenic amino acid, meaning it is not one of the twenty standard amino acids found in proteins. It is a structural analog of threonine, differing by an additional methylene group in its side chain. Its chemical formula is C5H11NO3. Homothreonine, like threonine, possesses a chiral center and exists as stereoisomers. The L-isomer is the more commonly studied form. It is synthesized in some organisms through specific metabolic pathways, though its biological roles are not as extensively characterized as those of proteinogenic amino acids. Research has explored its potential in various biochemical and pharmaceutical applications. For instance, it has been investigated as a potential building block for peptides with modified properties or as a component in drug design. Its presence has also been noted in certain natural products. Further research is ongoing to fully elucidate its biochemical significance and potential therapeutic uses.