farmakokineetiline
Farmakokineetiline refers to the study of how a drug moves through the body over time. It encompasses four main processes: absorption, distribution, metabolism, and excretion, often summarized by the acronym ADME. Absorption describes how the drug enters the bloodstream from its administration site. Distribution details how the drug spreads to various tissues and organs in the body. Metabolism refers to the chemical transformation of the drug, usually by enzymes, into different substances called metabolites. Excretion is the process by which the body eliminates the drug and its metabolites, primarily through urine and feces. Understanding these farmakokineetiline processes is crucial for determining appropriate drug dosages, dosing intervals, and routes of administration to achieve desired therapeutic effects while minimizing adverse reactions. It helps predict drug concentrations in the body at different times and guides the development of new medications.