erytromycin
Erythromycin is a macrolide antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial protein synthesis, specifically by binding to the 50S ribosomal subunit and preventing the formation of the 70S ribosome. This inhibits the growth and reproduction of bacteria. Erythromycin is effective against a wide range of Gram-positive bacteria, including Streptococcus, Staphylococcus, and Corynebacterium species. It is also active against some Gram-negative bacteria, such as Haemophilus influenzae and Legionella pneumophila. The drug is available in various forms, including oral tablets, oral suspension, and intravenous injection. Erythromycin is generally well-tolerated, but like all antibiotics, it can cause side effects such as gastrointestinal upset, nausea, and diarrhea. In some cases, it may also cause more serious side effects, such as allergic reactions or liver toxicity. Erythromycin should be used with caution in patients with liver or kidney disease, as well as in pregnant or breastfeeding women. It is important to complete the full course of treatment, even if symptoms improve, to ensure that the infection is fully eradicated.