endoteliinireseptorityyppiä
Endoteliinireseptorityyppiä refers to the different types of receptors that bind to endothelin. Endothelin is a potent vasoconstrictor peptide that plays a crucial role in regulating blood pressure and vascular tone. There are two main types of endothelin receptors, known as ETA and ETB receptors.
ETA receptors are primarily found in vascular smooth muscle cells and mediate the vasoconstrictive effects of
ETB receptors are distributed in various tissues, including endothelial cells, smooth muscle cells, and kidney cells.
The distinct roles of ETA and ETB receptors have made them targets for therapeutic interventions. For example,