endokannabinoidi
Endocannabinoids are a class of lipid-based neurotransmitters that are synthesized "on-demand" within the central and peripheral nervous systems of vertebrates. These molecules are endogenous ligands for cannabinoid receptors, primarily CB1 and CB2. The term "endocannabinoid" is derived from "endogenous cannabinoid," reflecting their natural production within the body and their structural and functional similarity to phytocannabinoids found in the cannabis plant.
The two best-characterized endocannabinoids are anandamide (AEA) and 2-arachidonoylglycerol (2-AG). Anandamide, whose name is derived from
The endocannabinoid system (ECS) is a complex signaling network that plays a crucial role in maintaining homeostasis.
Research into the endocannabinoid system has revealed its involvement in numerous physiological and pathological conditions, leading