ekstravaskulaarsed

Extravascular refers to anything located or occurring outside of a blood vessel. This term is commonly used in medical contexts, particularly in pathology and pharmacology. In pathology, extravascular substances are those that have escaped from their normal vascular compartment. For example, bleeding can lead to extravascular accumulation of red blood cells. Similarly, inflammation can cause the leakage of plasma proteins and white blood cells into the interstitial space, which is an extravascular area.

In pharmacology, the term extravascular administration refers to a route of drug delivery that does not involve injection directly into a blood vessel, such as oral, topical, or transdermal administration. These routes contrast with intravascular administration, which includes intravenous and intra-arterial injections. The absorption and distribution of a drug after extravascular administration can be influenced by various physiological factors. Understanding the extravascular space is crucial for diagnosing and treating many medical conditions, as well as for designing effective drug therapies. It encompasses all tissues and fluids outside the circulatory system.