The core structure of a dicarboxylic acid is defined by the presence of two carboxyl groups spaced along the carbon skeleton. The distance between the groups, the size of the carbon chain, and the substitution pattern determine the physical and chemical properties. Naming follows systematic IUPAC conventions, but many common acids have trivial names such as oxalic (two carbons), succinic (four carbons), glutaric (five carbons), and adipic (six carbons). Cyclic dicarboxylic acids include maleic, fumaric, and meso‑malonic acids.
Common examples of dicarboxylic acids have wide industrial significance. Oxalic acid is used as a cleaning agent and bleaching component; succinic acid serves as a precursor to solvents and nylon resins; glutaric acid is employed in polymer synthesis and pharmaceuticals; adipic acid is a key monomer in nylon‑6,6 production; maleic acid is used in the manufacture of acrylic resins and synthesizing pharmaceutical intermediates. Many of these acids are also found naturally in fruits, vegetables, and metabolic pathways in living organisms.
Applications of dicarboxylic acids encompass polymer chemistry, where they act as crosslinking agents or chain extenders. They are used in the production of plasticizers, coatings, adhesives, food additives, and solvent systems. In the pharmaceutical sector, they serve as intermediates in drug synthesis and as excipients. Agricultural formulations sometimes incorporate dicarboxylic acids to enhance nutrient availability or to act as chelating agents.
Handling dicarboxylic acids requires attention to safety. They are corrosive to skin and metal surfaces and can cause respiratory irritation when airborne. Laboratory exposure limits are governed by OSHA and other regulatory bodies. Environmental biodegradability varies; for instance, succinic acid is readily metabolized by microorganisms, whereas adipic acid may accumulate in aquatic systems. Proper storage, disposal, and use of personal protective equipment mitigate risks and align with current chemical safety standards.