dihomogammalinolensyre

Dihomogammalinolensyre, often abbreviated as DGLA, is a three double bond omega-6 fatty acid. It is a 20-carbon polyunsaturated fatty acid, meaning it has a chain of 20 carbon atoms and multiple carbon-carbon double bonds. Its chemical structure is cis-5,8,11-eicosatrienoic acid. DGLA is an intermediate in the metabolic pathway that converts linoleic acid into arachidonic acid. It is found in various plant oils, including borage oil, evening primrose oil, and black currant seed oil.

Within the body, DGLA can be converted into other fatty acids, most notably arachidonic acid, by the enzyme delta-5 desaturase. It can also be converted into prostaglandins, specifically prostaglandin E1 (PGE1), which is known for its anti-inflammatory and vasodilatory properties. The balance between DGLA and arachidonic acid metabolism is considered important for maintaining inflammatory homeostasis. Research has explored the potential health benefits of DGLA supplementation, particularly in relation to inflammatory conditions, although more definitive studies are needed.