daptomysiini
Daptomysiini, known in English as daptomycin, is a cyclic lipopeptide antibiotic produced by Streptomyces roseosporus. It is used to treat certain Gram-positive infections and is administered exclusively by intravenous infusion.
The antibiotic exerts its bactericidal effect through a calcium-dependent interaction with bacterial cell membranes. Daptomysiini inserts
Its activity is primarily against Gram-positive bacteria. It is active against many strains of methicillin-resistant Staphylococcus
Common approved indications include complicated skin and skin structure infections (cSSSI) and bacteremia, including right-sided infective
Adverse effects include myopathy and an elevated risk of rhabdomyolysis, particularly when used with statins; creatine
Daptomysiini was discovered in the late 20th century and approved for medical use in the early 2000s.