cinaciguat
Cinaciguat is an investigational drug that acts as a stimulator of soluble guanylate cyclase (sGC). Soluble guanylate cyclase is an enzyme involved in the production of cyclic guanosine monophosphate (cGMP), a key signaling molecule that plays a role in various physiological processes, including vasodilation. By stimulating sGC, cinaciguat increases intracellular cGMP levels, which can lead to relaxation of smooth muscle cells and widening of blood vessels. This vasodilatory effect is the basis for its investigation in various cardiovascular conditions.
The primary therapeutic area for cinaciguat has been the treatment of heart failure. Specifically, it has been
Research into cinaciguat has also explored its potential in other conditions where vasodilation is a therapeutic