chemokinek
Chemokinek, also known as chemokines, are small secreted cytokines that direct the movement of circulating leukocytes and other cells by forming chemical gradients. They play essential roles in immune surveillance, development, inflammation, and tissue repair. Chemokinek are categorized into four main subfamilies based on the arrangement of their first two cysteine residues: CXC, CC, CX3C, and C. This grouping correlates with receptor usage and function; for example, many CXC chemokinek attract neutrophils, while CC chemokinek attract monocytes, T cells, and dendritic cells.
Chemokinek exert their effects by binding to chemokinek receptors, a family of G protein-coupled receptors expressed
Common chemokinek include CXCL8 (interleukin-8), CCL5 (RANTES), CCL2 (MCP-1), and CXCL12 (SDF-1), each with specific receptor