catalasebased

Catalase-based refers to systems that rely on the enzyme catalase to decompose hydrogen peroxide. This includes enzymes, immobilized materials, and devices that incorporate catalase activity or mimic it. The core reaction is 2 H2O2 → 2 H2O + O2, enabling rapid detoxification of hydrogen peroxide in biological and engineered contexts. Natural catalase is a heme-containing enzyme found in peroxisomes of most aerobic organisms and tends to work best near neutral pH and moderate temperatures.

Applications of catalase-based systems span several fields. In biosensing and diagnostics, catalase-based components can generate or respond to oxygen in a measurable way, supporting signal transduction or protective effects against reactive oxygen species. In environmental and industrial settings, catalase-based materials help remove residual hydrogen peroxide produced during processing or disinfection. In nanotechnology and micromotors, immobilized catalase or catalase-mimicking materials can use hydrogen peroxide as a fuel source to drive propulsion or facilitate targeted delivery, often by releasing oxygen bubbles as a byproduct.

Immobilization and integration are key design aspects. Catalase can be attached to surfaces, encapsulated in polymers or gels, or embedded in nanoparticles, with goals of enhanced stability, reusability, and compatibility with sensors or reactors. Practical use requires attention to pH, temperature, potential inhibitors, and the effects of oxygen evolution on device performance.

Measurement of catalase activity typically tracks oxygen production, depletion of hydrogen peroxide, or colorimetric changes in coupled assays. Common activity units include katal or enzyme units (U). Safety considerations center on handling hydrogen peroxide and managing gas evolution in closed systems. See also catalase, enzyme immobilization, and peroxide sensing.