anthranilic

Anthranilic is an adjective used in chemistry to describe compounds related to anthranilic acid, which is also known as 2-aminobenzoic acid. The term appears in the names of derivatives such as anthranilic acid itself, anthranilamide (2-aminobenzamide), and various anthranilate esters and salts. Anthranilic derivatives are common building blocks in organic synthesis due to the presence of adjacent amino and carboxyl functional groups on an aromatic ring.

Anthranilic acid is an ortho-substituted benzoic acid that features both a carboxyl group and an amino group on neighboring carbon atoms. This arrangement enables a range of chemical transformations, including conversion to isatoic anhydride and subsequent elaboration into heterocycles, amides, esters, and other derivatives. The anthranilate motif is also found in dyes, pigments, and pharmaceutical intermediates, where it serves as a versatile starting material or building block.

In terms of production and preparation, anthranilic acid and related anthranilate compounds can be synthesized by multiple routes. Industrially, anthranilic acid is typically derived from o-nitrobenzoic acid via catalytic reduction, or accessed through transformations of related intermediates such as isatoic derivatives. These routes provide access to a broad family of anthranilate-based compounds used in research and manufacturing.

Safety and handling: Anthranilic compounds can be irritants and may pose health risks if ingested, inhaled, or absorbed. They should be handled with appropriate personal protective equipment, good laboratory practices, and proper waste disposal.