angiogenézu

Angiogenesis is the physiological process through which new blood vessels form from pre-existing ones. This complex, tightly regulated process is essential for growth and development, as well as for wound healing and tissue repair. In healthy adults, angiogenesis is typically dormant, but it can be reactivated under specific circumstances. The process is initiated by a signal from a tissue that is experiencing low oxygen levels or is undergoing rapid growth. This signal triggers endothelial cells, the cells that line blood vessels, to begin to proliferate and migrate. These cells then form a new vessel sprout, which can grow towards the source of the signal. As the sprout elongates, it can branch and fuse with other sprouts, eventually forming a new, functional blood vessel network. Angiogenesis is a critical factor in many biological processes. During embryonic development, it is responsible for establishing the vascular system. In adults, it plays a vital role in repairing damaged tissues and enabling the growth of the corpus luteum during the menstrual cycle. However, dysregulated angiogenesis is implicated in a number of diseases. For instance, uncontrolled angiogenesis can fuel the growth of tumors by providing them with the blood supply they need to proliferate and metastasize. Conversely, insufficient angiogenesis can impair wound healing and contribute to conditions like peripheral artery disease. Understanding the intricate mechanisms of angiogenesis is crucial for developing therapeutic strategies to treat diseases characterized by abnormal blood vessel formation.