ampho

Ampho is not a standalone term with a single fixed meaning in most standard references. Rather, it appears as a combining form derived from the Greek amphi-, meaning "both" or "on both sides." In scientific terminology, ampho- signals duality or dual properties and is often seen in terms describing substances or systems with two complementary aspects.

In practice, the more common spelling is amphi-, and ampho- can appear as a historical or variant prefix in the formation of certain words or in transliterations. Examples of the broader logic include amphipathic, where a molecule has both hydrophilic and hydrophobic regions, and ampholyte, a molecule that can function as an acid or a base depending on pH. These terms illustrate how the ampho-/amphi- prefix communicates dual or opposing characteristics within a single entity.

In pharmacology, ampho is sometimes used informally as shorthand for amphotericin B, a potent antifungal medication. Amphotericin B binds to ergosterol in fungal cell membranes, forming pores that disrupt membrane integrity and cause cell death. It is used for serious systemic fungal infections and certain parasitic infections, and is available in multiple formulations, including conventional amphotericin B deoxycholate and lipid-based formulations designed to reduce toxicity. Adverse effects can be significant, particularly nephrotoxicity and electrolyte imbalances, so therapy requires careful monitoring and dose adjustments.

Because ampho has multiple potential meanings depending on context, it is best interpreted from surrounding text. Related terms include amphipathic, ampholyte, amphoteric, amphipod, and amphotericin B.