adipocytic

Adipocytic is an adjective used to describe anything related to adipocytes, the fat-storing cells of adipose tissue. Adipocytes originate from mesenchymal cells and are specialized for lipid storage and endocrine signaling. White adipocytes contain a single large lipid droplet and a displaced nucleus, while brown adipocytes have multiple small lipid droplets and numerous mitochondria that enable heat generation. Beige adipocytes can develop within white fat under certain conditions, acquiring brown-like properties.

In histology and pathology, adipocytic is used to characterize cells, tissues, or tumors with adipocyte features. Examples include lipomas, benign tumors composed of mature adipocytes, and liposarcomas, malignant tumors showing adipocytic differentiation. Adipocytic differentiation is also discussed in the context of adipogenesis, where precursor cells mature into adipocytes during development or in regenerative processes.

Adipocytic features contribute to the overall function of adipose tissue, which not only stores energy but also secretes adipokines such as leptin and adiponectin, influencing metabolism, appetite, and immune responses. The term helps distinguish tissues and lesions with prominent adipocyte components from non-adipocytic connective tissues.