Xq24

Xq24 is a cytogenetic designation for a region on the long arm of the human X chromosome. It denotes band 24 in the Xq (the long arm) region and is used in karyotype descriptions and genetic testing to locate genes and structural features on the X chromosome. The region lies within the X chromosome’s q arm and is understood to contain multiple genetic elements, including both protein-coding and non-coding sequences. The exact gene content and regulatory landscape of Xq24 can vary depending on the genome reference build, so coordinates are typically provided in base-pair terms for modern assemblies. Genetic alterations in Xq24, such as deletions, duplications, or sequence variants in resident genes, have been reported in association with a range of X-linked and neurodevelopmental phenotypes, though disease links depend on the specific variant and its extent. Diagnostic approaches—including karyotyping, fluorescence in situ hybridization (FISH), chromosomal microarray analysis, and sequencing—can detect abnormalities in this region. Xq24 remains a focus of study in human genetics to better understand X-linked inheritance patterns and the functions of the genes located there.