Tioereduktáz

Tioereduktáz is an enzyme that plays a role in biological redox reactions. Specifically, it catalyzes the reduction of thioredoxin. Thioredoxin is a small protein found in all living organisms that participates in a variety of cellular processes, including DNA synthesis, DNA repair, and antioxidant defense. The enzyme tioereduktáz utilizes reducing power, often from NADPH, to reduce the disulfide bond in oxidized thioredoxin, thereby regenerating its active, reduced form. This regeneration is crucial for thioredoxin to continue its function within the cell. The enzyme's activity is essential for maintaining cellular redox homeostasis. Disruptions in tioereduktáz function or expression can lead to oxidative stress and have been implicated in various disease states. Understanding the structure and catalytic mechanism of tioereduktáz is an area of ongoing research in biochemistry and molecular biology. Its involvement in fundamental cellular pathways makes it a significant target for scientific investigation.