ThrombinLösung

ThrombinLösung refers to a solution containing thrombin. Thrombin is a serine protease, a crucial enzyme in the blood coagulation cascade. It plays a pivotal role in converting soluble fibrinogen into insoluble fibrin, which forms the meshwork of a blood clot. Thrombin is produced from its precursor, prothrombin, by the action of activated factor X (Xa) in the presence of factor V.

In a medical context, ThrombinLösung is often used topically to control bleeding. It can be applied directly to wounds or surgical sites to promote rapid clot formation. This application is particularly useful in situations where conventional methods of hemostasis are difficult or insufficient, such as during certain surgical procedures or in cases of capillary oozing. ThrombinLösung can be derived from human plasma or produced recombinantly. Its use is subject to specific indications and contraindications, and it is typically administered by trained healthcare professionals. It is important to note that the term "Lösung" is German for "solution," hence ThrombinLösung literally translates to thrombin solution.