Tatpathway
Tatpathway, or twin-arginine translocation pathway, is a protein export system found in many bacteria, and in the chloroplasts of plants and some archaea. It uniquely transports fully folded proteins across the cytoplasmic membrane, unlike the Sec pathway, which generally translocates unfolded polypeptides.
In bacteria the machinery comprises TatA, TatB, and TatC. TatC serves as the initial receptor that recognizes
Translocation is energized by the proton motive force across the inner membrane; ATP is not required. The
Substrates include a range of periplasmic and membrane-associated enzymes, many of which carry cofactors or metal